Calliope  Tsoupaki was born  in Piraeus, Greece, in May  1963.

First she studied piano and music theory at the Hellinicon Conservatory in Athens and later she joined the composition classes of Yannis Ioanithis. After she received her piano diploma, she continued her study in composition with Louis Andriessen at the Royal Conservatory of the Hague, in the Netherlands, where she graduated in December 1992